CRG Scientific Sessions
22/06/201812:00MARIE CURIEPRBB-CRG SessionsErez LiebermanDepartment of Genetics at the Baylor College of Medicine, Texas USA"A 3D code in the human genome"Host: Postdocs Students (CRG)Abstract:Stretched out from end-to-end, the human genome – a sequence of 3 billion chemical letters inscribed in a
molecule called DNA – is over 2 meters long. Famously, short stretches of DNA fold into a double helix, which
wind around histone proteins to form the 10nm fiber. But what about longer pieces? Does the genome’s fold
influence function? How does the information contained in such an ultra-dense packing even remain
In this talk, I describe our work...
29/06/201812:00MARIE CURIEPRBB-CRG SessionsMartin WeigtInstitut de Biologie, Paris FR"Protein sequence landscapes : From genomic data via statistical inference to structure prediction and de novo design"Host: Cedric Notredame (CRG)Abstract:Over the last years, biological research has been revolutionized by experimental high-throughput techniques. Unprecedented amounts of data are accumulating, causing an urgent need to develop data-driven modeling approaches to unveil information hidden in raw data, thereby helping to increase our understanding of complex biological systems. To give a specific example, proteins show a remarkable degree of structural...