Genetic Systems

Group Leader:


September 2009- ICREA Research Professor

December 2006- Group Leader, EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation, Barcelona.

2004-2006 Postdoctoral Fellow, Fraser Lab, The Wellcome Trust Sanger Institute

2004 PhD University of Cambridge

2000 BA Natural Sciences, University of Cambridge 

Our lab is part of the EMBL/CRG Systems Biology Unit.

We are funded by the European Research Council (ERC),  the EMBL-CRG Program, MICINN, AGAUR, ERASySBio+, and ICREA.

We are located in the Centre for Genomic Regulation which has a beautiful beachfront location in the Barcelona Biomedical Research Park.

Group News
Ben Lehner awarded a Consolidator Grant of the European Research Council (15/01/2014) 
Ben Lehner, head of the Genetic Systems research group and ICREA research professor at the Centre for Genomic Regulation (CRG), in Barcelona, ​​has just been awarded a Consolidator Grant from the European Research Council (ERC), for his project "Individual robustness in development and c
The effects of genetic variation in space and time (09/01/2014) 
CRG researchers describe in a paper published in Nature that many genetic differences between individuals influence the dynamic patterns of how genes are switched on or off during development. The research will contribute to the understanding of how the differences in our genomes affect dynamic proc
Ben Lehner, receives the Eppendorf Award for Young Investigators (11/06/2013) 
Ben Lehner has won the 2013 Eppendorf Young Investigator Award. The official Award ceremony took place at the EMBL Advanced Training Centre in Heidelberg, Germany, on June 6, 2013.

To what extent is it possible to predict the phenotypic differences amongst individuals from their completely sequenced genomes?  We use model organisms (yeast, worms) and computational analyses to understand when you can, and why you cannot, predict the biology of an individual from their genome sequence.  Individuals are thankfully all different, and our aim is to understand how these differences originate in the interactions between genetic, environmental, life history, parental and stochastic sources of variation.

Publications in the CRG database
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Group Members