Design of Biological Systems

Group Leader:


1981 Biology Sciences, Universidad Complutense de Madrid (Spain)
1982 Master of Sciences, Universidad Complutense de Madrid (Spain).
1985 Ph.D. in Biochemistry, Universidad Complutense de Madrid (Spain).
1987 Postdoctoral, Center of Mollecuar Biology (CSIC-UAM), Universidad Autónoma de Madrid (Spain).
1991 Postdoctoral, Cambridge University (Great Britain).
2001-2005 Head of Dpt., Dpt. Structural & Computational Biology, EMBL (Germany).
2005-present ICREA Research Professor and Group Leader at the Center for Genomic Regulation, Barcelona (Spain)
2005-June 2011 Coordinator of the Systems Biology Program at the Center for Genomic Regulation, Barcelona (Spain)
2006-present Director of the EMBL/CRG Systems Biology Research Unit at the Centre for Genomic Regulation, Barcelona (Spain)
July 2011-present Director of the Centre for Genomic Regulation, Barcelona (Spain)

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In our group we are aiming at a quantitative understanding of biological systems to an extent that one is able to predict systemic features and with the hope to rational design and modify their behaviour.  This applies to any system comprising biological components that is more than the mere sum of its components, or, in other words, the addition of the individual components results in systemic properties that could not be predicted by considering the components individually.  By achieving this objective we are aiming at new global understanding and treatment of human diseases in which the target will not be a single molecule but a network.  For this purpose in our group we develop on one hand new software and theoretical approximations to understand complex systems and on the other we do experiments to validate our predictions.

You can find more information about our group and our research project on our website

Research Lines
Publications in the CRG database

Group Members

Kiel, Christina
Martínez, Cira
Serrano, Luis
Yus, Eva